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Services
Antibody-producing cell lines maintenance
Contamination, cell line drift, growth issues?P.A.R.I.S diagnoses and treats your cell lines to ensure an optimal antibody production.
Mycoplasma test, sterility control, viability control, secretion test, ... lead to a customized treatment: mycoplasma eradication, boost, cloning, culture media adaptation.
Mycoplasma testing and removal service
P.A.R.I.S daily manages antibody-producing cell lines.
We test your supernatant sample or your cell banks from frozen vials.
I your cell banks are contaminated by mycoplasma, we propose an adapted removal program.
Antibody sequencing
Sequencing of variable regions of heavy and light chains of your antibodies.
Timeline: 4 to 6 weeks.
Chimeric antibody generation service
Enhance similarity to human at reasonable costs.
P.A.R.I.S proposes a service of antibody chimerization. Our technology preserves the specificity and affinity of the antibody toward the antigen whereas significantly reduces the immunogenicity of the antibody in humans.
P.A.R.I.S works from any isotype and you choose the final isotype: IgA or IgG.
Chimeric monoclonal antibody development
Do you wish to do without restraint of human serum for the calibration and positive control of your in vitro diagnostic kits?
Do you need an antibody with human heavy chain constant regions for functional testing?
P.A.R.I.S offers a service based on an exclusive technology to develop chimeric antibodies from transgenic mice.
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