Chimeric monoclonal antibody development

Do you wish to do without restraint of human serum for the calibration and positive control of your in vitro diagnostic kits?

Do you need an antibody with human heavy chain constant regions for functional testing? 

P.A.R.I.S offers a service based on an exclusive technology to develop chimeric antibodies from transgenic mice.

P.A.R.I.S conducts a standard program for monoclonal antibody development with transgenic mice. You directly obtain chimeric antibodies.

The program does not length more than a murine monoclonal antibody development.

You choose the final isotype: IgA or IgG.

You obtain stable antibodies with low immunogenicity and immediatly own the effector functions of human antibodies.

You already have murine antibodies?

P.A.R.I.S assumes the chimerization of your antibodies >>

Tell us your needs, we will make a program proposition as soon as possible >>